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Protein Coding Gene : Tnfsf13 tumor necrosis factor (ligand) superfamily, member 13

Primary Identifier  MGI:1916833 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  69583
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable receptor ligand activity. Acts upstream of or within immunoglobulin mediated immune response; positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; and positive regulation of cell population proliferation. Located in external side of plasma membrane. Is expressed in future midbrain; nervous system; renal vasculature; retina outer nuclear layer; and spleen. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to human TNFSF13 (TNF superfamily member 13).
PHENOTYPE: Homozygous null mice are viable and fertile. No apparent defects of the immune system have been reported. [provided by MGI curators]
  • synonyms:
  • tumor necrosis factor (ligand) superfamily, member 13,
  • TRDL1,
  • APRIL,
  • RIKEN cDNA 2310026N09 gene,
  • TALL2,
  • Tnfsf13,
  • 2310026N09Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For