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Protein Coding Gene : Tnk1 tyrosine kinase, non-receptor, 1

Primary Identifier  MGI:1930958 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  83813
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables ATP binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in negative regulation of Ras protein signal transduction and negative regulation of cell growth. Located in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; pituitary gland; respiratory system; and thymus. Orthologous to human TNK1 (tyrosine kinase non receptor 1).
PHENOTYPE: Mice either heterozygous or homozygous for a knock-out allele develop spontaneous tumors, including lymphomas and carcinomas, at high rates. [provided by MGI curators]
  • synonyms:
  • Kos1,
  • Tnk1b,
  • tyrosine kinase, non-receptor, 1,
  • Tnk1,
  • Tnk1a

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For