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Protein Coding Gene : Slc13a2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

Primary Identifier  MGI:1276558 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  20500
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables sodium:dicarboxylate symporter activity and succinate transmembrane transporter activity. Involved in succinate transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Is expressed in 4-cell stage embryo; nervous system; and sensory organ. Orthologous to human SLC13A2 (solute carrier family 13 member 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased Kreb cycle intermediates in the urine but otherwise have normal kidney function and response to ischemia-reperfusion injury and caloric restriction. [provided by MGI curators]
  • synonyms:
  • Nadc1,
  • mNaDC-1,
  • solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2,
  • Slc13a2,
  • sodium/dicarboxylate co-transporter,
  • sodium/dicarboxylate cotransporter 1

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For