| Primary Identifier | MGI:107504 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 14607 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables receptor ligand activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and positive regulation of insulin secretion. Acts upstream of or within several processes, including adult locomotory behavior; exploration behavior; and memory. Predicted to be located in neuronal cell body. Predicted to be active in extracellular space. Is expressed in gut. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human GIP (gastric inhibitory polypeptide). PHENOTYPE: Mice homozygous for a knock-out allele exhibit obesity and insulin hypersecretion but normal K-cell number when fed a high fat diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
