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Protein Coding Gene : Pcgf2 polycomb group ring finger 2

Primary Identifier  MGI:99161 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  22658
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chromatin binding activity. Acts upstream of or within several processes, including cellular response to hydrogen peroxide; chordate embryonic development; and negative regulation of transcription by RNA polymerase II. Located in nuclear body. Part of PRC1 complex and sex chromatin. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; eye; and genitourinary system. Orthologous to human PCGF2 (polycomb group ring finger 2).
PHENOTYPE: Homozygous null mutants exhibit multiple abnormalities of the axial skeleton (including homeotic transformations), grow markedly slower, and die either perinatally or between 3-6 weeks of age depending on genetic background. [provided by MGI curators]
  • synonyms:
  • Zfp144,
  • zinc finger protein 144,
  • Pcgf2,
  • polycomb group ring finger 2,
  • Rnf110,
  • ring finger protein 110,
  • mel-18,
  • Mel18,
  • MGD-MRK-15913

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For