Primary Identifier | MGI:109584 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 19134 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to act upstream of or within RNA splicing; mRNA processing; and phosphorylation. Located in chromosome. Is expressed in several structures, including cerebral cortex; early conceptus; oocyte; and pancreas epithelium. Orthologous to human PRP4K (pre-mRNA processing factor kinase PRP4K). PHENOTYPE: Mice homozygous for a knock-out allele show failure of blastocyst formation, increased cell death, absent inner cell mass proliferation, and complete embryonic lethality before implantation. [provided by MGI curators] |