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Protein Coding Gene : Prpf4b pre-mRNA processing factor 4B

Primary Identifier  MGI:109584 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  19134
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to act upstream of or within RNA splicing; mRNA processing; and phosphorylation. Located in chromosome. Is expressed in several structures, including cerebral cortex; early conceptus; oocyte; and pancreas epithelium. Orthologous to human PRP4K (pre-mRNA processing factor kinase PRP4K).
PHENOTYPE: Mice homozygous for a knock-out allele show failure of blastocyst formation, increased cell death, absent inner cell mass proliferation, and complete embryonic lethality before implantation. [provided by MGI curators]
  • synonyms:
  • MGC:5960,
  • MGD-MRK-39583,
  • Prpk,
  • pre-mRNA processing factor 4B,
  • Prpf4b,
  • pre-mRNA protein kinase,
  • Prp4k,
  • Prp4

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For