Primary Identifier | MGI:90168 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 28199 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to human DCAF11 (DDB1 and CUL4 associated factor 11). PHENOTYPE: Mice homozygous for a null allele exhibit gradual telomere erosion with successive generations and compromised hematopoietic stem cell activity. [provided by MGI curators] |