| Primary Identifier | MGI:1933111 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 80287 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including deaminase activity; identical protein binding activity; and zinc ion binding activity. Involved in negative regulation of viral genome replication and retrotransposon silencing. Acts upstream of or within hematopoietic progenitor cell differentiation; regulation of defense response to virus; and regulation of viral life cycle. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Orthologous to several human genes including APOBEC3B (apolipoprotein B mRNA editing enzyme catalytic subunit 3B); APOBEC3D (apolipoprotein B mRNA editing enzyme catalytic subunit 3D); and APOBEC3F (apolipoprotein B mRNA editing enzyme catalytic subunit 3F). PHENOTYPE: Mice homozygous for a gene trapped allele display more rapid and extensive spread of viral infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
