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Protein Coding Gene : Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2

Primary Identifier  MGI:1926555 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  60597
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables kinesin binding activity. Involved in several processes, including behavioral fear response; dendrite morphogenesis; and excitatory postsynaptic potential. Acts upstream of or within JNK cascade. Located in cytoplasm; neuronal cell body; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Used to study autism spectrum disorder. Orthologous to human MAPK8IP2 (mitogen-activated protein kinase 8 interacting protein 2).
PHENOTYPE: Mice homozygous for a null allele are smaller in size and exhibit male infertility. Mice homozygous for a different knock-out allele exhibit behavioral and cerebellar transmission deficits. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW049958,
  • Jip2,
  • 3230402N03Rik,
  • JNK-interacting protein,
  • MGI:2146184,
  • mitogen-activated protein kinase 8 interacting protein 2,
  • MGI:2146077,
  • RIKEN cDNA 3230402N03 gene,
  • IB2,
  • R75148,
  • AW049958,
  • MGI:2146319,
  • expressed sequence AI847694,
  • MGI:1914671,
  • expressed sequence R75148,
  • AI847694,
  • Mapk8ip2

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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3 Involved In Mutations

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0 Transgenic Expressors

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Disease

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