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Protein Coding Gene : Zbtb20 zinc finger and BTB domain containing 20

Primary Identifier  MGI:1929213 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  56490
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of glycolytic process; and regulation of gene expression. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study Alzheimer's disease. Orthologous to human ZBTB20 (zinc finger and BTB domain containing 20).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit growth retardation, disrupted homeostasis, and premature death. [provided by MGI curators]
  • synonyms:
  • HOF,
  • MGI:1915064,
  • zinc finger and BTB domain containing 20,
  • RIKEN cDNA 1300017A20 gene,
  • D16Wsu73e,
  • RIKEN cDNA A930017C21 gene,
  • A930017C21Rik,
  • Zfp288,
  • MGD-MRK-33985,
  • 7330412A13Rik,
  • zinc finger protein 288,
  • MGI:3057146,
  • RIKEN cDNA 7330412A13 gene,
  • MGI:1925687,
  • MGI:106293,
  • Zbtb20,
  • DNA segment, Chr 16, Wayne State University 73, expressed,
  • MGI:1925393,
  • 1300017A20Rik

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