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Protein Coding Gene : Dcp2 decapping mRNA 2
Primary Identifier  MGI:1917890 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  70640
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity and 5'-3' RNA exonuclease activity. Involved in mRNA catabolic process. Predicted to be located in cell junction; cytoplasmic ribonucleoprotein granule; and nucleoplasm. Predicted to be part of RISC complex. Predicted to be active in P-body. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human DCP2 (decapping mRNA 2).
PHENOTYPE: Mice homozygous for a gene trapped allele are viable and fertile. Mice homozygous for a null allele exhibit male infertility with reduced sperm numbers and motility. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2410015D23 gene,
  • expressed sequence AL118268,
  • Dcp2,
  • 2410015D23Rik,
  • MGI:1913674,
  • RIKEN cDNA 5730537H01 gene,
  • 5730537H01Rik,
  • MGI:3035096,
  • decapping mRNA 2,
  • AL118268
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