| Primary Identifier | MGI:1346880 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 26403 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including ATP binding activity; JUN kinase kinase kinase activity; and enzyme binding activity. Predicted to be involved in several processes, including JNK cascade; cell cycle G1/S phase transition; and positive regulation of JNK cascade. Predicted to act upstream of or within phosphorylation. Predicted to be located in microtubule. Predicted to be active in centrosome. Is expressed in blood vessel; brain; and embryo. Orthologous to human MAP3K11 (mitogen-activated protein kinase kinase kinase 11). PHENOTYPE: Homozygotes for a targeted or spontaneous mutation display a pattern of dark red stripes of thin dorsal epithelium during pre-wean development, and necrotic dental pulp has been reported for the spontaneous mutant. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
