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Protein Coding Gene : Patl2 protein associated with topoisomerase II homolog 2 (yeast)

Primary Identifier  MGI:1914828 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  67578
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA binding activity and translation repressor activity. Acts upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Located in P-body and nucleus. Used to study ovarian disease. Orthologous to human PATL2 (PAT1 homolog 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit defects in oocyte maturation, abnormal female meiosis I arrest, reduced female fertility, and impaired fertilization affecting preimplantation embryo development. Male fertility is normal. [provided by MGI curators]
  • synonyms:
  • 4930424G05Rik,
  • RIKEN cDNA 4930424G05 gene,
  • Patl2,
  • Pat1a,
  • protein associated with topoisomerase II homolog 2 (yeast)

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For