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Protein Coding Gene : Usp50 ubiquitin specific peptidase 50
Primary Identifier  MGI:1922333 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  75083
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable cysteine-type deubiquitinase activity. Acts upstream of or within positive regulation of NLRP3 inflammasome complex assembly; positive regulation of interleukin-1 beta production; and positive regulation of interleukin-18 production. Predicted to be located in centrosome; cytoplasm; and nucleus. Predicted to be active in several cellular components, including dendritic spine; midbody; and postsynaptic density. Orthologous to human USP50 (ubiquitin specific peptidase 50).
  • synonyms:
  • Usp50,
  • ubiquitin specific peptidase 50,
  • 1700086G18Rik,
  • RIKEN cDNA 4930511O11 gene,
  • 4930511O11Rik,
  • RIKEN cDNA 1700086G18 gene,
  • MGI:1923866
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Features --> Cross References

Genome

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2 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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Literature

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