| Primary Identifier | MGI:104747 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 18767 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables cAMP-dependent protein kinase inhibitor activity and protein kinase A catalytic subunit binding activity. Acts upstream of or within negative regulation of protein import into nucleus; negative regulation of transcription by RNA polymerase II; and regulation of G2/M transition of mitotic cell cycle. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human PKIA (cAMP-dependent protein kinase inhibitor alpha). PHENOTYPE: Homozygotes for a targeted null mutation exhibit decreased basal and isoproterenol-induced phosphoenolpyruvate carboxykinase expression in muscle, but are phenotypically normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
