| Primary Identifier | MGI:107335 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 12164 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cytokine activity. Involved in several processes, including BMP signaling pathway; diet induced thermogenesis; and germ cell development. Acts upstream of or within spermatogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in ectoplacental cone; embryo; extraembryonic ectoderm; metanephros; and trophectoderm. Orthologous to human BMP8B (bone morphogenetic protein 8b). PHENOTYPE: Incidence of lethality among homozygous null mutants is variable depending on genetic background and due to allantoic and embryonic abnormalities. Heterozygous and surviving homozygous males exhibit varying degrees of germ cell deficiency and infertility, also background dependent. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
