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Protein Coding Gene : Cpeb2 cytoplasmic polyadenylation element binding protein 2

Primary Identifier  MGI:2442640 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  231207
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables nucleic acid binding activity and ribosome binding activity. Involved in cellular response to hypoxia; negative regulation of cytoplasmic translation; and regulation of translation at synapse, modulating synaptic transmission. Acts upstream of or within negative regulation of translational elongation. Located in cytoplasm and ribosome. Is active in glutamatergic synapse. Is expressed in central nervous system; early conceptus; and olfactory epithelium. Orthologous to human CPEB2 (cytoplasmic polyadenylation element binding protein 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit early postnatal lethality, decreased heart rate, and increased parasympathetic signaling leading to increased pulmonary acetylcholine level, bronchoconstriction, severe apnea, and abnormal breathing patterns. [provided by MGI curators]
  • synonyms:
  • cytoplasmic polyadenylation element binding protein 2,
  • Cpeb2,
  • RIKEN cDNA A630055H10 gene,
  • A630055H10Rik

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Genome

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0 Canonical

0 CDSs

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6 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Disease

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