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Protein Coding Gene : Oas1a 2'-5' oligoadenylate synthetase 1A
Primary Identifier  MGI:2180860 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  246730
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Involved in purine nucleotide biosynthetic process. Acts upstream of or within negative regulation of viral process. Predicted to be located in mitochondrion; nucleus; and ribosome. Predicted to be active in cytosol; membrane; and nucleoplasm. Predicted to colocalize with cytoplasm. Is expressed in appendicular skeleton; axial skeleton; lower jaw; and testis. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1).
  • synonyms:
  • 2'-5' oligoadenylate synthetase 1A,
  • L3,
  • Oas1a
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3 Involved In Mutations

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