| Primary Identifier | MGI:99600 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 11669 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including NADH binding activity; carboxylesterase activity; and nitroglycerin reductase activity. Involved in regulation of dopamine biosynthetic process and regulation of serotonin biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; artery disease (multiple); diabetes mellitus (multiple); and liver disease (multiple). Orthologous to human ALDH2 (aldehyde dehydrogenase 2 family member). PHENOTYPE: Homozygous mutation of this gene results in the absence of oxidation activity in the mitochondria. Mice homozygous for a different allele exhibit decreased litter size. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
