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Protein Coding Gene : Rasa4 RAS p21 protein activator 4
Primary Identifier  MGI:1858600 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  54153
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GTPase activator activity. Predicted to be involved in cellular response to calcium ion; intracellular signal transduction; and negative regulation of Ras protein signal transduction. Predicted to be located in cytosol. Predicted to colocalize with plasma membrane. Is expressed in trigeminal ganglion. Orthologous to several human genes including RASA4 (RAS p21 protein activator 4).
PHENOTYPE: Mice homozygous for disruptions in this gene display an increased sensitivity to bacterial infections which involves reduced phagocyte function. [provided by MGI curators]
  • synonyms:
  • MGI:2141155,
  • EST AA793972,
  • AA793972,
  • RAS p21 protein activator 4,
  • expressed sequence BB079060,
  • expressed sequence AW112107,
  • BB079060,
  • AW112107,
  • Rasa4,
  • MGI:2141261
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5 Pathways

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Disease

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