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Protein Coding Gene : Alkbh4 alkB homolog 4, lysine demethylase

Primary Identifier  MGI:1919291 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  72041
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables broad specificity oxidative DNA demethylase activity. Involved in positive regulation of gene expression, epigenetic. Predicted to be located in cytoplasm and nucleus. Predicted to be active in contractile ring and midbody. Orthologous to human ALKBH4 (alkB homolog 4, lysine demethylase).
PHENOTYPE: Mice homozygous for a targeted mutation exhibit lethality prior to weaning. Mice homozygous for a floxed allele activated in mouse embryonic fibroblasts exhibit decreased migration and impaired cytokinesis. [provided by MGI curators]
  • synonyms:
  • 2010004B12Rik,
  • alkB homolog 4, lysine demethylase,
  • Abj4,
  • Alkbh4,
  • RIKEN cDNA 2010004B12 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

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0 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For