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Protein Coding Gene : Snx8 sorting nexin 8

Primary Identifier  MGI:2443816 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  231834
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable identical protein binding activity and phosphatidylinositol binding activity. Predicted to be involved in early endosome to Golgi transport and intracellular protein transport. Predicted to act upstream of or within protein transport. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of retromer complex. Predicted to be active in early endosome membrane. Is expressed in cerebral cortex ventricular layer and small intestine. Orthologous to human SNX8 (sorting nexin 8).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to lethal infection by Listeria monocytogenes. [provided by MGI curators]
  • synonyms:
  • B130023O14Rik,
  • Snx8,
  • RIKEN cDNA B130023O14 gene,
  • sorting nexin 8

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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