| Primary Identifier | MGI:1350929 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 27053 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity and identical protein binding activity. Predicted to be involved in several processes, including asparagine biosynthetic process; cellular response to glucose starvation; and positive regulation of mitotic cell cycle. Predicted to act upstream of or within amino acid biosynthetic process and glutamine metabolic process. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human ASNS (asparagine synthetase (glutamine-hydrolyzing)). PHENOTYPE: Mice homozygous for a hypomophic allele exhibit structural brain abnormalities, including enlarged ventricles and reduced cortical thickness, and deficits in short- and long-term memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
