| Primary Identifier | MGI:1097714 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 20893 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables DNA-binding transcription factor binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and E-box binding activity. Involved in circadian regulation of gene expression and entrainment of circadian clock by photoperiod. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human BHLHE40 (basic helix-loop-helix family member e40). PHENOTYPE: Homozygous mutation of this gene results in impaired immune function and hyperplasia of the lymphoid organs. Aging mutant animals exhibit autoimmune disease. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
