| Primary Identifier | MGI:107619 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 15465 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including G protein-coupled serotonin receptor activity; calcium ion transmembrane transporter activity; and histamine binding activity. Acts upstream of or within memory; regulation of synaptic plasticity; and visual learning. Predicted to be located in cytosol. Predicted to be active in dendrite and plasma membrane. Is expressed in brain; stomach; and uterus. Orthologous to human HRH1 (histamine receptor H1). PHENOTYPE: Homozygous null mutants show decrease in exploratory behavior, diurnal activity, aggression, anxiety, serotonin release, respiratory reaction to temperature and leptin response. Natural variants affect B. pertussis induced vasoactive amine sensitization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
