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Protein Coding Gene : Lgi4 leucine-rich repeat LGI family, member 4

Primary Identifier  MGI:2180197 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  243914
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in regulation of myelination. Acts upstream of or within adult locomotory behavior and neurogenesis. Located in extracellular space. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-1 and childhood absence epilepsy. Orthologous to human LGI4 (leucine rich repeat LGI family member 4).
PHENOTYPE: Homozygous mutant animals have an abnormal posture where the forelimbs are flexed and rotated inwards. The peripheral nervous system is delayed in myelination. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-2019,
  • clp,
  • MGI:88420,
  • Lgi4,
  • claw paw,
  • leucine-rich repeat LGI family, member 4

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For