| Primary Identifier | MGI:107559 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 20352 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon extension involved in axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to act upstream of or within cell differentiation and nervous system development. Located in plasma membrane and synapse. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including back musculature; central nervous system; peripheral nervous system ganglion; and retina. Orthologous to human SEMA4B (semaphorin 4B). PHENOTYPE: Mice homozygous for a gene trap allele exhibit normal cerebellar morphology. Mice homozygous for a knock-out allele exhibit enhanced memory response by way of increased IgE and IgG1 serum levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
