| Primary Identifier | MGI:1928765 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 56788 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables hedgehog family protein binding activity. Acts upstream of or within several processes, including positive regulation of chondrocyte proliferation; positive regulation of osteoblast differentiation; and positive regulation of smoothened signaling pathway. Located in extracellular space. Is expressed in several structures, including cardiovascular system; central nervous system; neural ectoderm; sensory organ; and skeleton. Orthologous to human SCUBE2 (signal peptide, CUB domain and EGF like domain containing 2). PHENOTYPE: Mice homozygous for a null mutation are smaller than controls. Mice also exhibit defective endochondral bone formation and impaired Ihh-mediated chondrocyte differentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
