|  Help  |  About  |  Contact Us

Protein Coding Gene : Tspan32 tetraspanin 32

Primary Identifier  MGI:1350360 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  27027
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Acts upstream of or within several processes, including defense response to protozoan; integrin-mediated signaling pathway; and negative regulation of leukocyte activation. Located in cell surface. Part of integrin alphaIIb-beta3 complex. Is expressed in several structures, including central nervous system; ganglia; immune system; placenta; and tongue. Orthologous to human TSPAN32 (tetraspanin 32).
PHENOTYPE: Mice homozygous for a gene trap null mutation exhibit normal hematopoiesis, hemolytic and granulopoitic responses. B cells exhibit normal proliferative responses while T cells demonstrate enhanced proliferation upon T cell receptor stimulation. [provided by MGI curators]
  • synonyms:
  • DNA segment, Chr 7, Wayne State University 37, expressed,
  • pan hematopoietic expression,
  • MGI:2142216,
  • Art-1,
  • Tspan32,
  • Tssc6,
  • tumor-suppressing subchromosomal transferable fragment 6,
  • MGI:106446,
  • expressed sequence BB235973,
  • Phemx,
  • MGD-MRK-34140,
  • expressed sequence AW208513,
  • tetraspanin 32,
  • AW208513,
  • MGI:1861715,
  • MGI:2142302,
  • BB235973,
  • D7Wsu37e

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For