Primary Identifier | MGI:3648770 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 546143 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in axoneme assembly; cilium movement; and determination of left/right symmetry. Is active in axonemal A tubule inner sheath. Is expressed in embryo and node. Orthologous to human PIERCE2 (piercer of microtubule wall 2). PHENOTYPE: Mice homozygous for a null allele exhibit reduced nodal cilia beating frequency without disruption of left right axis patterning. [provided by MGI curators] |