| Primary Identifier | MGI:1333878 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 22437 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable actin filament binding activity and filamin binding activity. Acts upstream of or within several processes, including Notch signaling pathway; muscle cell development; and negative regulation of cell population proliferation. Located in adherens junction and fascia adherens. Is expressed in several structures, including heart; musculature; and tail somite. Used to study hypertrophic cardiomyopathy. Orthologous to human XIRP1 (xin actin binding repeat containing 1). PHENOTYPE: Homozygous mice exhibit cardiac hypertrophy and a disruption of cardiac intercalated disc structure and myofilament abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
