Primary Identifier | MGI:1924536 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 77286 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ATPase activator activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleolus and nucleoplasm. Is expressed in limb mesenchyme and ureter. Orthologous to human NKRF (NFKB repressing factor). PHENOTYPE: Homozygous female and hemizygous male null mice are viable and fertile with normal inflammatory responses, response to infection, peripheral blood cell populations and skin morphology. [provided by MGI curators] |