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Protein Coding Gene : Nkrf NF-kappaB repressing factor

Primary Identifier  MGI:1924536 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  77286
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ATPase activator activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleolus and nucleoplasm. Is expressed in limb mesenchyme and ureter. Orthologous to human NKRF (NFKB repressing factor).
PHENOTYPE: Homozygous female and hemizygous male null mice are viable and fertile with normal inflammatory responses, response to infection, peripheral blood cell populations and skin morphology. [provided by MGI curators]
  • synonyms:
  • MGI:2148002,
  • AW124770,
  • expressed sequence C80287,
  • RIKEN cDNA 9430034D17 gene,
  • expressed sequence AW124770,
  • Nkrf,
  • MGI:2148062,
  • 9430034D17Rik,
  • C80287,
  • NF-kappaB repressing factor

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Canonical gene --> Transcripts in specific strains.

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