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Protein Coding Gene : Zfx zinc finger protein X-linked

Primary Identifier  MGI:99211 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  22764
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin insulator sequence binding activity. Acts upstream of or within several processes, including oocyte development; ovarian follicle development; and parental behavior. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of chromatin. Predicted to be active in chromosome. Is expressed in several structures, including 4-cell stage embryo; central nervous system; genitourinary system; ileum; and spleen. Orthologous to human ZFX (zinc finger protein X-linked).
PHENOTYPE: Male mice hemizygous or female mice homozygous for one knock-out allele exhibit reduced size, viability, and gametes. Another knock-out allele generates mice that exhibit embryonic lethality associated with abnormal extraembryonic tissue and reduction in hematopoietic stem cells. [provided by MGI curators]
  • synonyms:
  • Zfx6,
  • zinc finger protein X-linked 6,
  • MGD-MRK-15963,
  • zinc finger protein X-linked,
  • Zfx5,
  • Zfx,
  • Zfx5,6,
  • MGI:1096556,
  • zinc finger protein X-linked 5,
  • MGI:1096553

Features --> Cross References

Genome

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1 Transgenic Expressors

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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