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Protein Coding Gene : Tex11 testis expressed gene 11

Primary Identifier  MGI:1933237 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  83558
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in meiotic gene conversion and reciprocal meiotic recombination. Acts upstream of or within several processes, including male gonad development; meiotic nuclear division; and negative regulation of apoptotic process. Located in central element. Colocalizes with synaptonemal complex. Is expressed in oocyte and testis. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 2. Orthologous to human TEX11 (testis expressed 11).
PHENOTYPE: Mice homozygous for a knockout allele exhibit abnormal male meiosis. Mice homozygous for a conditional knockout exhibit male infertility and reduced female fecundity due to abnormal meiosis following cre recombination. [provided by MGI curators]
  • synonyms:
  • Tex11,
  • expressed sequence BB024231,
  • 4930565P14Rik,
  • MGI:2442304,
  • BB024231,
  • MGI:2148032,
  • testis expressed gene 11,
  • RIKEN cDNA 4930565P14 gene

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Genome

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4 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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Genes --> Homologs

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Disease

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