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Protein Coding Gene : Tlr13 toll-like receptor 13

Primary Identifier  MGI:3045213 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  279572
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables identical protein binding activity and rRNA binding activity. Involved in innate immune response and toll-like receptor 13 signaling pathway. Acts upstream of or within MyD88-dependent toll-like receptor signaling pathway; regulation of MAPK cascade; and response to virus. Located in endosome. Is expressed in vibrissa.
PHENOTYPE: Macrophages isolated from mice carrying an ENU-induced mutation respond normally to known TLR ligands and can contain various viral infections; however, mice carrying this allele have not been tested for immune responses in vivo. [provided by MGI curators]
  • synonyms:
  • LOC279572,
  • Tlr13,
  • MGI:2147911,
  • AI666735,
  • toll-like receptor 13,
  • Gm713,
  • gene model 713, (NCBI),
  • MGI:2685559,
  • expressed sequence AI666735

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