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Protein Coding Gene : Brwd3 bromodomain and WD repeat domain containing 3

Primary Identifier  MGI:3029414 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  382236
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 93. Orthologous to human BRWD3 (bromodomain and WD repeat domain containing 3).
PHENOTYPE: Male chimeras hemizygous for a gene trapped allele exhibit short tail buds, microcephaly and, in some cases, embryonic growth retardation. [provided by MGI curators]
  • synonyms:
  • Brwd3,
  • MGI:2443903,
  • Brodl,
  • bromo domain-containing protein disrupted in leukemia,
  • gene model 596, (NCBI),
  • Gm596,
  • D030064D06Rik,
  • RIKEN cDNA D030064D06 gene,
  • bromodomain and WD repeat domain containing 3,
  • MGI:2685442,
  • LOC236955

Features --> Cross References

Genome

Sequence Feature Displayer

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0 CDSs

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0 Involved In Mutations

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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