| Primary Identifier | MGI:1196284 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 14605 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Acts upstream of or within negative regulation of activation-induced cell death of T cells and response to osmotic stress. Located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; nervous system; sensory organ; and viscerocranium. Orthologous to human TSC22D3 (TSC22 domain family member 3). PHENOTYPE: Hemizygous null males show mild deficits in sodium handling, weight reduction, hyperinsulinemia, resistance to liver steatosis, and sterility associated with azoospermia, testis dysplasia, Leydig cell hyperplasia, male germ cell apoptosis, arrested meiosis, and high FSH and testosterone levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
