| Primary Identifier | MGI:3042378 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 333605 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in positive regulation of synapse structural plasticity and postsynaptic actin cytoskeleton organization. Predicted to be located in cell projection; cytoskeleton; and synapse. Predicted to be part of protein-containing complex. Predicted to be active in dendritic spine; glutamatergic synapse; and postsynaptic density. Is expressed in dorsal root ganglion; facial ganglion; lateral ventricle choroid plexus; metencephalon part of 4th ventricle choroid plexus; and trigeminal ganglion. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased inflammation-induced pain and thermal pain in a chronic pain model. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
