| Primary Identifier | MGI:107846 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 15469 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables histone methyltransferase activity and protein-arginine N-methyltransferase activity. Involved in RNA splicing and cardiac muscle tissue development. Acts upstream of or within in utero embryonic development. Located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and lung. Used to study cleft palate. Orthologous to human PRMT1 (protein arginine methyltransferase 1). PHENOTYPE: Embryos homozygous for a null mutation die before E6.5 and exhibit abnormal embryonic tissue morphology. Mice homozygous for a conditional allele activated in germ cells exhibit male infertility with azoospermia due to meiosis arrest at the leptotene or zygotene stage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
