| First Author | Ferrari S | Year | 1994 |
| Journal | J Biol Chem | Volume | 269 |
| Issue | 46 | Pages | 28803-8 |
| PubMed ID | 7961836 | Mgi Jnum | J:21498 |
| Mgi Id | MGI:69460 | Doi | 10.1016/s0021-9258(19)61977-0 |
| Citation | Ferrari S, et al. (1994) The mouse gene coding for high mobility group 1 protein (HMG1). J Biol Chem 269(46):28803-8 |
| abstractText | We have isolated an active gene encoding the mouse HMG1 protein among a multitude of cross-hybridizing sequences, which most likely are retrotransposed pseudogenes. The hmg1 gene contains five exons, of which the first is not translated, and the last contains a long 3'-untranslated sequence and three alternative polyadenylation sites. We found no evidence for a sequence encoding a membrane localization signal in the hmg1 gene, despite the presence of HMG1 protein on the surface of several cell types. The hmg1 promoter coincides with a CpG island, contains no TATA sequence, and derives the expression of reporter genes placed under its control. The hmg1 gene may be a member of a family of closely related genes but appears to be the major or the only active gene coding for HMG1 protein. |
