|  Help  |  About  |  Contact Us

Allele : Tg(CAG-WRN*K577M)5025Wcl transgene insertion 5025, Warren C Ladiges

Primary Identifier  MGI:3525073 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CAG-WRN*K577M)5025Wcl
Strain of Origin  C57BL/6 x C3H Is Recombinase  false
Is Wild Type  false
description 

This line is representative of three lines made, which include the 4128, 4998 and the 5025 lines.

molecularNote  The transgene is composed of a full length cDNA encoding human WRN with a mutation that alters lysine 577 to methionine expressed under the control of a cytomegalovirus enhancer and a chicken beta-actin promoter, and was followed by a rabbit beta-globin polyadenylation site.
  • mutations:
  • Insertion
  • synonyms:
  • K577-WRN,
  • Tg(ACTB-WRN*K577M)5025Wcl,
  • K577-WRN,
  • Tg(ACTB-WRN*K577M)5025Wcl,
  • Tg(CAG-WRN*K577M)5025Wcl,
  • Tg(CAG-WRN*K577M)5025Wcl
Quick Links:
 
Quick Links:
 

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories