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Allele : Cdkn1b<tm1Kin> cyclin dependent kinase inhibitor 1B; targeted mutation 1, Kei-ichi Nakayama

Primary Identifier	MGI:1888790	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cdkn1b
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A PGK-neomycin resistance cassette in reverse orientation replaced a 2.5kb sequence containing exons 1 and 2. This deletes the entire coding portion of the gene. Immunoblots of whole tissue lysates of the thymus demnonstrate the absence of protein product.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
p27<->,
p27<Kip1->,
p27<Kip1>,
p27<Kip1->,
p27<Kip1>,
p27<->

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

34 Publication categories

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