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Search results 1 to 100 out of 847 for Vangl2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication  
First Author: Bouali S
Year: 2022
Journal: Front Cell Dev Biol
Title: Vangl2 Promotes Hematopoietic Stem Cell Expansion.
Volume: 10
Pages: 760248
Publication  
First Author: Nagaoka T
Year: 2014
Journal: Sci Rep
Title: Vangl2 regulates E-cadherin in epithelial cells.
Volume: 4
Pages: 6940
GXD Expression
Probe: MGI:6715641
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6715649
Age: postnatal day 4
Image: 5A Vangl2 cKO
Note: Asymmetry of expression strongly reduced or randomized, and largely uncorrelated with follicle orientation.
Specimen Label: 5A Vangl2 cKO
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6715641
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6715649
Age: postnatal day 4
Image: 5B Vangl2 cKO
Note: Expression in epidermis surrounding hair follicle is highly disordered and does not align with follicles.
Specimen Label: 5B Vangl2 cKO
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6715641
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6715649
Age: postnatal day 4
Image: 5C Vangl2 cKO
Note: Asymmetry of expression strongly reduced or randomized, and largely uncorrelated with follicle orientation.
Specimen Label: 5C Vangl2 cKO
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:6715641
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752825
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6715649
Age: embryonic day 17.5
Image: 6C Vangl2 cKO
Note: Asymmetry of expression is highly reduced.
Specimen Label: 6C Vangl2 cKO
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:6715641
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6715649
Age: embryonic day 15.5
Image: 7D Vangl2 cKO
Note: Polarity of expression asymmetry in interfollicular epidermis strongly reduced; more uniformly distributed around cell cortex.
Specimen Label: 7D Vangl2 cKO
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1339624
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1877125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6715650
Age: embryonic day 17.5
Image: 6A Vangl2 cKO
Specimen Label: 6A Vangl2 cKO
Detected: true
Specimen Num: 2
Publication
First Author: Leung V
Year: 2016
Journal: Dev Neurobiol
Title: The planar cell polarity protein Vangl2 is required for retinal axon guidance.
Volume: 76
Issue: 2
Pages: 150-65
Publication
First Author: Seo HS
Year: 2017
Journal: Hum Mol Genet
Title: Bimodal regulation of Dishevelled function by Vangl2 during morphogenesis.
Volume: 26
Issue: 11
Pages: 2053-2061
Publication
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Volume: 19
Issue: 23
Pages: 4663-76
Publication
First Author: Robert BJA
Year: 2020
Journal: Cell Rep
Title: Vangl2 in the Dentate Network Modulates Pattern Separation and Pattern Completion.
Volume: 31
Issue: 10
Pages: 107743
Publication
First Author: Gong Y
Year: 2021
Journal: Dev Cell
Title: Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells.
Volume: 56
Issue: 14
Pages: 2103-2120.e9
Publication
First Author: Phillips HM
Year: 2005
Journal: Circ Res
Title: Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract.
Volume: 96
Issue: 3
Pages: 292-9
Publication
First Author: Guyot MC
Year: 2011
Journal: Dev Dyn
Title: A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene.
Volume: 240
Issue: 4
Pages: 839-49
Publication
First Author: Yang W
Year: 2017
Journal: Cell Res
Title: Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development.
Volume: 27
Issue: 12
Pages: 1466-1484
Publication
First Author: Hu Z
Year: 2023
Journal: Sci Adv
Title: VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.
Volume: 9
Issue: 25
Pages: eadg2339
Publication
First Author: Montcouquiol M
Year: 2003
Journal: Nature
Title: Identification of Vangl2 and Scrb1 as planar polarity genes in mammals.
Volume: 423
Issue: 6936
Pages: 173-7
Publication
First Author: Nagaoka T
Year: 2019
Journal: Sci Rep
Title: Vangl2 interaction plays a role in the proteasomal degradation of Prickle2.
Volume: 9
Issue: 1
Pages: 2912
Publication  
First Author: Shi D
Year: 2016
Journal: Mech Dev
Title: Dynamics of planar cell polarity protein Vangl2 in the mouse oviduct epithelium.
Volume: 141
Pages: 78-89
Publication
First Author: Smith P
Year: 2019
Journal: Sci Rep
Title: VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland.
Volume: 9
Issue: 1
Pages: 7079
Publication
First Author: Liu J
Year: 2008
Journal: J Neurogenet
Title: Effects of retinoic acid on the expressions of Vangl1 and vangl2 in mouse fetuses.
Volume: 22
Issue: 3
Pages: 167-79
Publication
First Author: Escobedo N
Year: 2013
Journal: Development
Title: Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity.
Volume: 140
Issue: 14
Pages: 3008-17
Publication
First Author: Phillips HM
Year: 2008
Journal: Circ Res
Title: Non-cell-autonomous roles for the planar cell polarity gene Vangl2 in development of the coronary circulation.
Volume: 102
Issue: 5
Pages: 615-23
Publication
First Author: Tower-Gilchrist C
Year: 2019
Journal: Mol Biol Cell
Title: Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear.
Volume: 30
Issue: 18
Pages: 2422-2434
Publication
First Author: Thakar S
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation.
Volume: 114
Issue: 4
Pages: E610-E618
Publication
First Author: Kim YS
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation.
Volume: 120
Issue: 20
Pages: e2302937120
Publication    
First Author: Dos-Santos Carvalho S
Year: 2020
Journal: Elife
Title: Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth.
Volume: 9
Publication
First Author: Gao B
Year: 2011
Journal: Dev Cell
Title: Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2.
Volume: 20
Issue: 2
Pages: 163-76
Publication
First Author: Brzóska HŁ
Year: 2016
Journal: Kidney Int
Title: Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.
Volume: 90
Issue: 6
Pages: 1274-1284
Publication
First Author: Shafer B
Year: 2011
Journal: Dev Cell
Title: Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance.
Volume: 20
Issue: 2
Pages: 177-91
Publication  
First Author: Galea GL
Year: 2018
Journal: Dis Model Mech
Title: Vangl2 disruption alters the biomechanics of late spinal neurulation leading to spina bifida in mouse embryos.
Volume: 11
Issue: 3
Publication
First Author: Derish I
Year: 2020
Journal: PLoS One
Title: Differential role of planar cell polarity gene Vangl2 in embryonic and adult mammalian kidneys.
Volume: 15
Issue: 3
Pages: e0230586
Publication
First Author: Giese AP
Year: 2012
Journal: Development
Title: Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear.
Volume: 139
Issue: 20
Pages: 3775-85
Publication
First Author: Montcouquiol M
Year: 2006
Journal: J Neurosci
Title: Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.
Volume: 26
Issue: 19
Pages: 5265-75
Publication
First Author: Suriben R
Year: 2009
Journal: Nat Genet
Title: Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak.
Volume: 41
Issue: 9
Pages: 977-85
Publication  
First Author: Cheong SS
Year: 2020
Journal: Front Cell Dev Biol
Title: The Planar Polarity Component VANGL2 Is a Key Regulator of Mechanosignaling.
Volume: 8
Pages: 577201
Publication
First Author: Merte J
Year: 2010
Journal: Nat Cell Biol
Title: Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure.
Volume: 12
Issue: 1
Pages: 41-6; sup pp 1-8
Publication
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis.
Volume: 19
Issue: 11
Pages: 2251-67
Publication
First Author: Mahaffey JP
Year: 2013
Journal: Development
Title: Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo.
Volume: 140
Issue: 6
Pages: 1262-71
Publication  
First Author: Najarro EH
Year: 2020
Journal: Development
Title: Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.
Volume: 147
Issue: 19
Publication
First Author: Zhang H
Year: 2015
Journal: Gene
Title: The homologous genes Vangl1 and Vangl2 are required for embryo implantation in the uterus of mice during early pregnancy.
Volume: 555
Issue: 2
Pages: 140-9
Publication
First Author: Galea GL
Year: 2021
Journal: Nat Commun
Title: Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice.
Volume: 12
Issue: 1
Pages: 1159
Publication
First Author: Nagaoka T
Year: 2023
Journal: Sci Rep
Title: Functional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the developing neural tube and cochlear sensory epithelium.
Volume: 13
Issue: 1
Pages: 3905
Publication
First Author: Torban E
Year: 2007
Journal: Gene Expr Patterns
Title: Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation.
Volume: 7
Issue: 3
Pages: 346-54
Publication  
First Author: Ghimire SR
Year: 2018
Journal: Development
Title: A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.
Volume: 145
Issue: 12
Publication
First Author: Li S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity.
Volume: 108
Issue: 6
Pages: 2264-9
Publication
First Author: Yin H
Year: 2012
Journal: PLoS One
Title: Comparison of phenotypes between different vangl2 mutants demonstrates dominant effects of the Looptail mutation during hair cell development.
Volume: 7
Issue: 2
Pages: e31988
Publication
First Author: Rocque BL
Year: 2015
Journal: J Am Soc Nephrol
Title: Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury.
Volume: 26
Issue: 3
Pages: 576-86
Publication
First Author: Glasco DM
Year: 2012
Journal: Dev Biol
Title: The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.
Volume: 369
Issue: 2
Pages: 211-22
Publication
First Author: Wansleeben C
Year: 2010
Journal: Development
Title: Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b.
Volume: 137
Issue: 7
Pages: 1067-73
Publication
First Author: Chen B
Year: 2013
Journal: Genet Mol Res
Title: Loop-tail phenotype in heterozygous mice and neural tube defects in homozygous mice result from a nonsense mutation in the Vangl2 gene.
Volume: 12
Issue: 3
Pages: 3157-65
Publication
First Author: Ren DD
Year: 2013
Journal: Dev Dyn
Title: Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice.
Volume: 242
Issue: 12
Pages: 1454-65
Publication
First Author: Torban E
Year: 2004
Journal: J Biol Chem
Title: Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.
Volume: 279
Issue: 50
Pages: 52703-13
Publication
First Author: De Castro SCP
Year: 2018
Journal: Hum Mol Genet
Title: Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice.
Volume: 27
Issue: 24
Pages: 4218-4230
Publication
First Author: Buono R
Year: 2012
Journal: Stem Cells
Title: Nitric oxide sustains long-term skeletal muscle regeneration by regulating fate of satellite cells via signaling pathways requiring Vangl2 and cyclic GMP.
Volume: 30
Issue: 2
Pages: 197-209
Publication
First Author: Ghimire SR
Year: 2019
Journal: J Neurosci
Title: Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by Type II Spiral Ganglion Neurons.
Volume: 39
Issue: 41
Pages: 8013-8023
GXD Expression    
Probe: MGI:4948304
Assay Type: Western blot
Annotation Date: 2020-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6460053
Age: postnatal day 14
Image: 5 S1
Specimen Label: Vangl2 cKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2449010
Assay Type: Western blot
Annotation Date: 2020-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6460054
Age: postnatal day 14
Image: 5 S1
Specimen Label: Vangl2 cKO
Detected: true
Specimen Num: 2
Publication
First Author: Wang Y
Year: 2006
Journal: J Neurosci
Title: The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells.
Volume: 26
Issue: 8
Pages: 2147-56
Publication
First Author: Yoshioka T
Year: 2013
Journal: FEBS Lett
Title: Vangl2, the planar cell polarity protein, is complexed with postsynaptic density protein PSD-95 [corrected].
Volume: 587
Issue: 10
Pages: 1453-9
Publication
First Author: Delaunay D
Year: 2014
Journal: Cell Rep
Title: Mitotic spindle asymmetry: a Wnt/PCP-regulated mechanism generating asymmetrical division in cortical precursors.
Volume: 6
Issue: 2
Pages: 400-14
Publication
First Author: Wu Z
Year: 2016
Journal: Cell Tissue Res
Title: Altered tooth morphogenesis after silencing the planar cell polarity core component, Vangl2.
Volume: 366
Issue: 3
Pages: 617-621
Publication
First Author: Papakrivopoulou E
Year: 2018
Journal: J Pathol
Title: Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury.
Volume: 246
Issue: 4
Pages: 485-496
Publication
First Author: Yuan J
Year: 2018
Journal: Nat Commun
Title: Tridimensional visualization reveals direct communication between the embryo and glands critical for implantation.
Volume: 9
Issue: 1
Pages: 603
Publication
First Author: Williams M
Year: 2014
Journal: Dev Cell
Title: Distinct apical and basolateral mechanisms drive planar cell polarity-dependent convergent extension of the mouse neural plate.
Volume: 29
Issue: 1
Pages: 34-46
Publication
First Author: Jarjour AA
Year: 2020
Journal: Glia
Title: The formation of paranodal spirals at the ends of CNS myelin sheaths requires the planar polarity protein Vangl2.
Volume: 68
Issue: 9
Pages: 1840-1858
Publication
First Author: Gravel M
Year: 2010
Journal: Biochemistry
Title: Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse.
Volume: 49
Issue: 16
Pages: 3445-55
Publication  
First Author: Feng B
Year: 2021
Journal: Sci Adv
Title: Planar cell polarity signaling components are a direct target of β-amyloid-associated degeneration of glutamatergic synapses.
Volume: 7
Issue: 34
Publication    
First Author: Stahley SN
Year: 2021
Journal: Elife
Title: Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes.
Volume: 10
Publication
First Author: Carroll EA
Year: 2003
Journal: Dev Biol
Title: Cordon-bleu is a conserved gene involved in neural tube formation.
Volume: 262
Issue: 1
Pages: 16-31
Publication  
First Author: Kim YS
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Cannabinoid and planar cell polarity signaling converges to direct placentation.
Volume: 118
Issue: 38
Publication  
First Author: Nychyk O
Year: 2022
Journal: Dis Model Mech
Title: Vangl2-environment interaction causes severe neural tube defects, without abnormal neuroepithelial convergent extension.
Volume: 15
Issue: 1
Publication
First Author: Pryor SE
Year: 2014
Journal: Development
Title: Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals.
Volume: 141
Issue: 16
Pages: 3153-8
Publication
First Author: Le Grand F
Year: 2009
Journal: Cell Stem Cell
Title: Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.
Volume: 4
Issue: 6
Pages: 535-47
Publication
First Author: Ross AJ
Year: 2005
Journal: Nat Genet
Title: Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates.
Volume: 37
Issue: 10
Pages: 1135-40
Publication
First Author: Belotti E
Year: 2012
Journal: PLoS One
Title: Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes.
Volume: 7
Issue: 9
Pages: e46213
Publication
First Author: Kimura-Yoshida C
Year: 2018
Journal: Nat Commun
Title: Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis.
Volume: 9
Issue: 1
Pages: 4059
Publication
First Author: Saburi S
Year: 2008
Journal: Nat Genet
Title: Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.
Volume: 40
Issue: 8
Pages: 1010-5
Publication
First Author: Yang X
Year: 2013
Journal: J Biol Chem
Title: SEC14 and spectrin domains 1 (Sestd1) and Dapper antagonist of catenin 1 (Dact1) scaffold proteins cooperatively regulate the Van Gogh-like 2 (Vangl2) four-pass transmembrane protein and planar cell polarity (PCP) pathway during embryonic development in mice.
Volume: 288
Issue: 28
Pages: 20111-20
Publication
First Author: Torban E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Genetic interaction between members of the Vangl family causes neural tube defects in mice.
Volume: 105
Issue: 9
Pages: 3449-54
Publication  
First Author: Almeida SM
Year: 2023
Journal: Dis Model Mech
Title: An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity.
Volume: 16
Issue: 8
Publication
First Author: El-Hassan AR
Year: 2018
Journal: Mamm Genome
Title: Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2.
Volume: 29
Issue: 3-4
Pages: 229-244
Publication
First Author: Chai G
Year: 2014
Journal: Nat Neurosci
Title: Celsr3 is required in motor neurons to steer their axons in the hindlimb.
Volume: 17
Issue: 9
Pages: 1171-9
Publication
First Author: Wang Y
Year: 2016
Journal: Development
Title: Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.
Volume: 143
Issue: 23
Pages: 4441-4451
Publication
First Author: Heydeck W
Year: 2011
Journal: Dev Dyn
Title: PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube.
Volume: 240
Issue: 8
Pages: 1938-48
Publication
First Author: Tissir F
Year: 2010
Journal: Nat Neurosci
Title: Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.
Volume: 13
Issue: 6
Pages: 700-7
Publication
First Author: Devenport D
Year: 2008
Journal: Nat Cell Biol
Title: Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles.
Volume: 10
Issue: 11
Pages: 1257-68
Publication
First Author: Orriss IR
Year: 2018
Journal: Sci Rep
Title: Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.
Volume: 8
Issue: 1
Pages: 3325
Publication
First Author: Macheda ML
Year: 2012
Journal: J Biol Chem
Title: The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling.
Volume: 287
Issue: 35
Pages: 29312-23