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Search results 201 to 300 out of 312 for Tlr5

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Type Details Score
Publication
17202381 | J:142618
First Author: Bagchi A
Year: 2007
Journal: J Immunol
Title: MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists.
Volume: 178
Issue: 2
Pages: 1164-71
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Publication
21918198 | J:179303
First Author: Porter GW
Year: 2011
Journal: J Immunol
Title: TLR agonists downregulate H2-O in CD8alpha- dendritic cells.
Volume: 187
Issue: 8
Pages: 4151-60
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Publication
29590614 | J:271255
First Author: Thackray LB
Year: 2018
Journal: Cell Rep
Title: Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections.
Volume: 22
Issue: 13
Pages: 3440-3453.e6
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Publication
21458307 | J:171379
First Author: Shi C
Year: 2011
Journal: Immunity
Title: Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands.
Volume: 34
Issue: 4
Pages: 590-601
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Publication
19933833 | J:157789
First Author: Hasegawa M
Year: 2010
Journal: Infect Immun
Title: Transitions in oral and intestinal microflora composition and innate immune receptor-dependent stimulation during mouse development.
Volume: 78
Issue: 2
Pages: 639-50
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Publication
22306056 | J:181331
First Author: Kirkland D
Year: 2012
Journal: Immunity
Title: B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage.
Volume: 36
Issue: 2
Pages: 228-38
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Publication
22466646 | J:184544
First Author: Rivas MN
Year: 2012
Journal: J Clin Invest
Title: MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice.
Volume: 122
Issue: 5
Pages: 1933-47
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Publication
17135446 | J:116763
First Author: Coban C
Year: 2007
Journal: Int Immunol
Title: Pathological role of Toll-like receptor signaling in cerebral malaria.
Volume: 19
Issue: 1
Pages: 67-79
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Publication
25210785 | J:337019
First Author: Zhang K
Year: 2014
Journal: PLoS Pathog
Title: Age-dependent enterocyte invasion and microcolony formation by Salmonella.
Volume: 10
Issue: 9
Pages: e1004385
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Publication
19806220 | J:154108
First Author: Raoust E
Year: 2009
Journal: PLoS One
Title: Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells.
Volume: 4
Issue: 10
Pages: e7259
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Publication
29097366 | J:252459
First Author: Hai Q
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Quantitative Trait Locus Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant.
Volume: 38
Issue: 1
Pages: 83-91
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Publication
28758900 | J:247855
First Author: Whitehead GS
Year: 2017
Journal: J Clin Invest
Title: TNF is required for TLR ligand-mediated but not protease-mediated allergic airway inflammation.
Volume: 127
Issue: 9
Pages: 3313-3326
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Publication
21239713 | J:169160
First Author: Enoksson M
Year: 2011
Journal: J Immunol
Title: Mast cells as sensors of cell injury through IL-33 recognition.
Volume: 186
Issue: 4
Pages: 2523-8
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Publication
23075849 | J:189217
First Author: Huber S
Year: 2012
Journal: Nature
Title: IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine.
Volume: 491
Issue: 7423
Pages: 259-63
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Publication
19382893 | J:150494
First Author: Kumar H
Year: 2009
Journal: Biochem J
Title: Pathogen recognition in the innate immune response.
Volume: 420
Issue: 1
Pages: 1-16
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Publication
21057511 | J:167323
First Author: Miao EA
Year: 2010
Journal: Nat Immunol
Title: Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.
Volume: 11
Issue: 12
Pages: 1136-42
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Publication
22323544 | J:181854
First Author: Lacroix-Lamandé S
Year: 2012
Journal: J Immunol
Title: Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome.
Volume: 188
Issue: 6
Pages: 2805-14
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Publication
22837383 | J:187389
First Author: Naik S
Year: 2012
Journal: Science
Title: Compartmentalized control of skin immunity by resident commensals.
Volume: 337
Issue: 6098
Pages: 1115-9
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Publication
27001940 | J:236744
 
First Author: Martino MM
Year: 2016
Journal: Nat Commun
Title: Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration.
Volume: 7
Pages: 11051
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Publication
24637670 | J:210311
 
First Author: Takemura N
Year: 2014
Journal: Nat Commun
Title: Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome.
Volume: 5
Pages: 3492
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Publication
32150572 | J:287406
First Author: Place DE
Year: 2020
Journal: PLoS Pathog
Title: Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.
Volume: 16
Issue: 3
Pages: e1008364
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Publication
20668698 | J:163082
First Author: Koh YS
Year: 2010
Journal: PLoS One
Title: MyD88-dependent signaling contributes to host defense against ehrlichial infection.
Volume: 5
Issue: 7
Pages: e11758
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Publication
27716507 | J:236522
First Author: Chudnovskiy A
Year: 2016
Journal: Cell
Title: Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Volume: 167
Issue: 2
Pages: 444-456.e14
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Publication
22297845 | J:181354
First Author: Henao-Mejia J
Year: 2012
Journal: Nature
Title: Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
Volume: 482
Issue: 7384
Pages: 179-85
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Publication
22666391 | J:187296
First Author: Kaul D
Year: 2012
Journal: PLoS One
Title: Expression of Toll-like receptors in the developing brain.
Volume: 7
Issue: 5
Pages: e37767
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Publication
31729371 | J:281617
First Author: Balounová J
Year: 2019
Journal: Nat Commun
Title: Toll-like receptor 2 expression on c-kit+ cells tracks the emergence of embryonic definitive hematopoietic progenitors.
Volume: 10
Issue: 1
Pages: 5176
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Publication
25681338 | J:274041
First Author: Onishi M
Year: 2015
Journal: J Immunol
Title: Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Volume: 194
Issue: 6
Pages: 2673-82
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Publication
28400473 | J:242009
First Author: Choo MK
Year: 2017
Journal: J Exp Med
Title: TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Volume: 214
Issue: 5
Pages: 1297-1311
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Publication
15921521 | J:101842
 
First Author: Norkina O
Year: 2005
Journal: BMC Genet
Title: Potential genetic modifiers of the cystic fibrosis intestinal inflammatory phenotype on mouse chromosomes 1, 9, and 10.
Volume: 6
Pages: 29
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Publication
17095659 | J:116164
First Author: Dequéant ML
Year: 2006
Journal: Science
Title: A complex oscillating network of signaling genes underlies the mouse segmentation clock.
Volume: 314
Issue: 5805
Pages: 1595-8
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Publication
- | J:342609
       
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
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Publication
25584886 | J:218897
First Author: Pfirschke C
Year: 2015
Journal: Cancer Cell
Title: Common TLR5 mutations control cancer progression.
Volume: 27
Issue: 1
Pages: 1-3
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Strain
MGI:5577116 | B6.129P2-Tlr5<tm1Aki>/Obs
Attribute String: targeted mutation, mutant strain, congenic
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Publication
21890657 | J:179325
First Author: Fukuzawa N
Year: 2011
Journal: J Immunol
Title: A TLR5 agonist inhibits acute renal ischemic failure.
Volume: 187
Issue: 7
Pages: 3831-9
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Publication
18209032 | J:131353
First Author: Ha H
Year: 2008
Journal: J Immunol
Title: Stimulation by TLR5 modulates osteoclast differentiation through STAT1/IFN-beta.
Volume: 180
Issue: 3
Pages: 1382-9
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Publication
30158114 | J:265838
First Author: Chakrabarty P
Year: 2018
Journal: J Exp Med
Title: TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.
Volume: 215
Issue: 9
Pages: 2247-2264
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Allele
Tlr5<em3(cre/ERT2)Smoc> | MGI:7292811
Name: toll-like receptor 5; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Allele
Tlr5<em4(cre)Smoc> | MGI:7292812
Name: toll-like receptor 5; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
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Publication
34434198 | J:345753
 
First Author: Logeswaran A
Year: 2021
Journal: Front Immunol
Title: Conjunctival Goblet Cell Responses to TLR5 Engagement Promote Activation of Local Antigen-Presenting Cells.
Volume: 12
Pages: 716939
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GO Term
GO:0034146 | toll-like receptor 5 signaling pathway
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GO Term
GO:0034148 | negative regulation of toll-like receptor 5 signaling pathway
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GO Term
GO:0034147 | regulation of toll-like receptor 5 signaling pathway
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GO Term
GO:0034149 | positive regulation of toll-like receptor 5 signaling pathway
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Publication
28827825 | J:248152
First Author: Forstnerič V
Year: 2017
Journal: PLoS Pathog
Title: The role of the C-terminal D0 domain of flagellin in activation of Toll like receptor 5.
Volume: 13
Issue: 8
Pages: e1006574
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Protein Domain
IPR001029 | Flagellin_N
Type: Domain
Description: Bacterial flagella are responsible for motility and chemotaxis []. They comprise a basal body, a hook and a filament, the latter accounting for 98% of the mass []. Flagellin is the subunit protein that polymerises to form the flagella [], the subunits being transported through the centre of the filament to the tip, where they then polymerise []. Both the N- and C-termini of the subunit protein, which are α-helical in structure [], are required to mediate polymerisation. Although no export or assembly, consensus sequences have been identified: Ala, Val, Leu, Ile, Gly, Ser, Thr, Asn, Gln and Asp tend to make up around 90% of the sequence, Cys and Trp being absent [].Flagellin plays a role in the activation of innate and adaptive immunity. It is an specific ligand for Toll-like receptor 5 (TLR5) in the host, which has lead to great interest to use it as adjuvant for vaccines [, , ]. The protein is also recognised by the intracellular NAIP5/NLRC4 inflammasome receptor []. This entry represents the N-terminal domain of Flagellin and similar bacterial proteins. This domain comes together with the C-terminal domain () to form the D0 and D1 structural domains []. These domains are responsible for the activation of TLR5 [, ].
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Publication
27339979 | J:233302
First Author: Birchenough GM
Year: 2016
Journal: Science
Title: A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion.
Volume: 352
Issue: 6293
Pages: 1535-42
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Publication
29768176 | J:277092
First Author: Pelka K
Year: 2018
Journal: Immunity
Title: The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Volume: 48
Issue: 5
Pages: 911-922.e7
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Publication
33046728 | J:299057
First Author: El Bissati K
Year: 2020
Journal: Sci Rep
Title: Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice.
Volume: 10
Issue: 1
Pages: 16984
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Publication
33784296 | J:304386
First Author: Pérez-Cruz M
Year: 2021
Journal: PLoS One
Title: The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced infection in cigarette smoke-exposed mice.
Volume: 16
Issue: 3
Pages: e0236216
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Publication
21525388 | J:173183
First Author: Fujimoto K
Year: 2011
Journal: J Immunol
Title: A new subset of CD103+CD8alpha+ dendritic cells in the small intestine expresses TLR3, TLR7, and TLR9 and induces Th1 response and CTL activity.
Volume: 186
Issue: 11
Pages: 6287-95
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Publication
16365459 | J:126245
First Author: Fu Y
Year: 2006
Journal: J Immunol
Title: Innate stimuli accentuate end-organ damage by nephrotoxic antibodies via Fc receptor and TLR stimulation and IL-1/TNF-alpha production.
Volume: 176
Issue: 1
Pages: 632-9
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Publication
17579072 | J:149411
First Author: Park JH
Year: 2007
Journal: J Immunol
Title: Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells.
Volume: 179
Issue: 1
Pages: 514-21
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Publication
25070848 | J:317662
First Author: Beswick EJ
Year: 2014
Journal: J Immunol
Title: TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cells.
Volume: 193
Issue: 5
Pages: 2218-29
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Publication
22158905 | J:181115
First Author: Marshall NA
Year: 2012
Journal: Cancer Res
Title: Immunotherapy with PI3K inhibitor and Toll-like receptor agonist induces IFN-γ+IL-17+ polyfunctional T cells that mediate rejection of murine tumors.
Volume: 72
Issue: 3
Pages: 581-91
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Publication
16785551 | J:134440
First Author: Jeyaseelan S
Year: 2006
Journal: J Immunol
Title: Toll/IL-1R domain-containing adaptor protein (TIRAP) is a critical mediator of antibacterial defense in the lung against Klebsiella pneumoniae but not Pseudomonas aeruginosa.
Volume: 177
Issue: 1
Pages: 538-47
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Publication
24486456 | J:210486
 
First Author: Deng R
Year: 2014
Journal: Exp Eye Res
Title: A potential link between bacterial pathogens and allergic conjunctivitis by dendritic cells.
Volume: 120
Pages: 118-26
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Publication
16936244 | J:143676
First Author: Skerrett SJ
Year: 2007
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Redundant Toll-like receptor signaling in the pulmonary host response to Pseudomonas aeruginosa.
Volume: 292
Issue: 1
Pages: L312-22
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Publication
20610649 | J:162244
First Author: Faham A
Year: 2010
Journal: J Immunol
Title: Antigen-containing liposomes engrafted with flagellin-related peptides are effective vaccines that can induce potent antitumor immunity and immunotherapeutic effect.
Volume: 185
Issue: 3
Pages: 1744-54
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Publication
17283089 | J:119764
First Author: Reiniger N
Year: 2007
Journal: Infect Immun
Title: Resistance to Pseudomonas aeruginosa chronic lung infection requires cystic fibrosis transmembrane conductance regulator-modulated interleukin-1 (IL-1) release and signaling through the IL-1 receptor.
Volume: 75
Issue: 4
Pages: 1598-608
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Publication
18490717 | J:136347
First Author: Sanders CJ
Year: 2008
Journal: J Immunol
Title: Both radioresistant and hemopoietic cells promote innate and adaptive immune responses to flagellin.
Volume: 180
Issue: 11
Pages: 7184-92
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Publication
24595157 | J:214532
First Author: Benmohamed F
Year: 2014
Journal: PLoS One
Title: Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection.
Volume: 9
Issue: 3
Pages: e90466
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Publication
18256364 | J:149925
First Author: Banas MC
Year: 2008
Journal: J Am Soc Nephrol
Title: TLR4 links podocytes with the innate immune system to mediate glomerular injury.
Volume: 19
Issue: 4
Pages: 704-13
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Publication
16670329 | J:131759
First Author: Yu Y
Year: 2006
Journal: J Immunol
Title: TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression.
Volume: 176
Issue: 10
Pages: 6194-201
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Publication
11490012 | J:114045
First Author: Supajatura V
Year: 2001
Journal: J Immunol
Title: Protective roles of mast cells against enterobacterial infection are mediated by Toll-like receptor 4.
Volume: 167
Issue: 4
Pages: 2250-6
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Publication
11739561 | J:114018
First Author: McCurdy JD
Year: 2001
Journal: J Leukoc Biol
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