|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 381 out of 381 for Cyld

<< First    < Previous  |  Next >    Last >>
0.025s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
32185393 | -
First Author: Dobson-Stone C
Year: 2020
Journal: Brain
Title: CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis.
Volume: 143
Issue: 3
Pages: 783-799
•
•
•
•
•
Publication
27307491 | J:235069
First Author: Wagner SA
Year: 2016
Journal: EMBO J
Title: SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.
Volume: 35
Issue: 17
Pages: 1868-84
•
•
•
•
•
Publication
32883697 | J:303965
First Author: Cui Z
Year: 2021
Journal: Mol Cancer Res
Title: CYLD Alterations in the Tumorigenesis and Progression of Human Papillomavirus-Associated Head and Neck Cancers.
Volume: 19
Issue: 1
Pages: 14-24
•
•
•
•
•
Interaction Experiment
Massoumi R (2006)
Description: Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.
•
•
•
•
•
Interaction Experiment
Nishanth G (2013)
Description: CYLD Enhances Severe Listeriosis by Impairing IL-6/STAT3-Dependent Fibrin Production.
•
•
•
•
•
Interaction Experiment
Zhu G (2021)
Description: TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
•
•
•
•
•
Allele
Cyld<+> | MGI:3048262
   
Name: CYLD lysine 63 deubiquitinase; wild type
•
•
•
•
•
Allele
Cyld<tm1Ref> | MGI:3714113
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1, Reinhard Fassler
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Allele
Cyld<tm1Lex> | MGI:3528559
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1, Lexicon Genetics
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Cyld<tm1Jdgl> | MGI:3722146
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1, Jian-Dong Li
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Cyld<tm1.1Gmos> | MGI:4819959
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1.1, George Mosialos
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Cyld<tm1.1Ozg> | MGI:7259786
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1.1, Ozgene
Allele Type: Targeted
Attribute String: Not Specified
•
•
•
•
•
Allele
Cyld<tm1.1Mpa> | MGI:5293377
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1.1, Manolis Pasparakis
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Cyld<tm1.1Attg> | MGI:5897343
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1.1, Adrian T Ting
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Cyld<em1Gpt> | MGI:7297647
Name: CYLD lysine 63 deubiquitinase; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Cyld<tm1.1Awai> | MGI:3761624
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1.1, Ari Waisman
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Cyld<em2Cya> | MGI:7583261
Name: CYLD lysine 63 deubiquitinase; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Cyld<em2Gpt> | MGI:7297648
Name: CYLD lysine 63 deubiquitinase; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Cyld<tm1Awai> | MGI:3761621
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1, Ari Waisman
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Cyld<tm1.2Gmos> | MGI:7343872
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1, George Mosialos
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Cyld<tm1Scs> | MGI:3664438
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1, Shao-Cong Sun
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Cyld<tm1Gmos> | MGI:4819961
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1, George Mosialos
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Interaction Experiment
Jin W (2008)
Description: Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice.
•
•
•
•
•
Interaction Experiment
Ahmed N (2011)
Description: The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.
•
•
•
•
•
Interaction Experiment
de Marval PM (2011)
Description: CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
•
•
•
•
•
Interaction Experiment
Wex K (2016)
Description: Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages.
•
•
•
•
•
Interaction Experiment
Schlicher L (2016)
Description: SPATA2 promotes CYLD activity and regulates TNF-induced NF-B signaling and cell death.
•
•
•
•
•
Interaction Experiment
Tang Y (2019)
Description: Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis.
•
•
•
•
•
Publication
34497368 | -
First Author: Zhu G
Year: 2021
Journal: Nat Cell Biol
Title: TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
Volume: 23
Issue: 9
Pages: 978-991
•
•
•
•
•
Strain
MGI:3715201 | B6.129-Cyld<tm1Ref>
Attribute String: targeted mutation, mutant strain, congenic
•
•
•
•
•
Allele
Cyld<tm1a(EUCOMM)Hmgu> | MGI:4842196
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
•
•
•
•
•
Strain
MGI:6439650 | B6;129S5-Cyld<tm1Lex>/Tac
Attribute String: mutant stock, targeted mutation
•
•
•
•
•
Strain
MGI:5562716 | STOCK Cyld<tm1.1Gmos>/Flmg
Attribute String: mutant stock, targeted mutation
•
•
•
•
•
Allele
Cyld<tm1e(EUCOMM)Hmgu> | MGI:4841589
Name: CYLD lysine 63 deubiquitinase; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Strain
MGI:7590249 | C57BL/6J-Cyld<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Strain
MGI:6352253 | C57BL/6NGpt-Cyld<em2Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Strain
MGI:7380763 | B6.Cg-Cyld<tm1.2Gmos>/Flmg
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: involves: 129S5/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: B6.129-Cyld
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: involves: 129 * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: involves: BALB/cJ
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld
Background: involves: C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Interaction Experiment
Takiuchi T (2014)
Description: Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.
•
•
•
•
•
Publication
20227366 | -
First Author: Tauriello DV
Year: 2010
Journal: Mol Cell
Title: Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl.
Volume: 37
Issue: 5
Pages: 607-19
•
•
•
•
•
Publication
26834734 | -
 
First Author: Wex K
Year: 2015
Journal: Front Immunol
Title: Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages.
Volume: 6
Pages: 650
•
•
•
•
•
Publication
27458237 | -
First Author: Schlicher L
Year: 2016
Journal: EMBO Rep
Title: SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death.
Volume: 17
Issue: 10
Pages: 1485-1497
•
•
•
•
•
Strain
MGI:7469494 | B6.Cg-Cyld<tm1Ref> Spata2<tm1(KOMP)Vlcg>
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld<+>
Background: B6.129-Cyld
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld Tg(CD19-cre/ERT2)1Cgn/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld Spata2/Spata2
Background: B6.Cg-Cyld Spata2
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld Tg(Alb1-cre)7Gsc/?
Background: involves: C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld Ripk3/Ripk3
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Strain
MGI:5293755 | B6.Cg-Cyld<tm1.1Mpa> Ikbkg<tm1.1Mpa> Tg(Vil1-cre)997Gum
Attribute String: congenic, mutant strain, targeted mutation, transgenic
•
•
•
•
•
Strain
MGI:5293525 | B6.Cg-Fadd<tm1Mpa> Cyld<tm1.1Mpa> Tg(Vil1-cre)997Gum
Attribute String: targeted mutation, transgenic, mutant strain, congenic
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld Ikbkg/? Tg(Vil1-cre)997Gum/?
Background: B6.Cg-Cyld Ikbkg Tg(Vil1-cre)997Gum
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld Ikbkg/Ikbkg Tg(Vil1-cre)997Gum/?
Background: B6.Cg-Cyld Ikbkg Tg(Vil1-cre)997Gum
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cyld/Cyld Fadd/Fadd Tg(Vil1-cre)997Gum/?
Background: B6.Cg-Fadd Cyld Tg(Vil1-cre)997Gum
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
17544371 | J:206918
First Author: Besse A
Year: 2007
Journal: Biochem Biophys Res Commun
Title: TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin ligase.
Volume: 359
Issue: 3
Pages: 660-4
•
•
•
•
•
Publication
17927961 | J:127324
First Author: Park ES
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene.
Volume: 363
Issue: 4
Pages: 971-7
•
•
•
•
•
Publication
27279133 | J:239894
 
First Author: Lin W
Year: 2016
Journal: Nat Commun
Title: Syndecan-4 negatively regulates antiviral signalling by mediating RIG-I deubiquitination via CYLD.
Volume: 7
Pages: 11848
•
•
•
•
•
Publication
23032187 | J:190394
First Author: Tokunaga F
Year: 2012
Journal: EMBO J
Title: Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation.
Volume: 31
Issue: 19
Pages: 3856-70
•
•
•
•
•
Publication
34853447 | J:344030
First Author: Hu Y
Year: 2022
Journal: Cell Death Differ
Title: Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1.
Volume: 29
Issue: 6
Pages: 1176-1186
•
•
•
•
•
Publication
27680285 | J:254125
 
First Author: Yu HC
Year: 2016
Journal: Sci Rep
Title: Blocking Notch signal in myeloid cells alleviates hepatic ischemia reperfusion injury by repressing the activation of NF-κB through CYLD.
Volume: 6
Pages: 32226
•
•
•
•
•
Publication
28973854 | J:256925
First Author: Ma Q
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Proteasome-independent polyubiquitin linkage regulates synapse scaffolding, efficacy, and plasticity.
Volume: 114
Issue: 41
Pages: E8760-E8769
•
•
•
•
•
Publication
23401595 | J:193681
First Author: Mc Guire C
Year: 2013
Journal: J Immunol
Title: Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination.
Volume: 190
Issue: 6
Pages: 2896-903
•
•
•
•
•
Publication
31366726 | J:280242
First Author: Uematsu A
Year: 2019
Journal: J Biol Chem
Title: The E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD.
Volume: 294
Issue: 38
Pages: 14135-14148
•
•
•
•
•
Publication
31762063 | J:286537
First Author: Yang XD
Year: 2020
Journal: EMBO J
Title: PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.
Volume: 39
Issue: 2
Pages: e102201
•
•
•
•
•
Publication
21811235 | J:200492
First Author: Niu J
Year: 2011
Journal: EMBO J
Title: LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO.
Volume: 30
Issue: 18
Pages: 3741-53
•
•
•
•
•
Publication
32560816 | J:302353
First Author: Zhu J
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Osteoclastic miR-301-b knockout reduces ovariectomy (OVX)-induced bone loss by regulating CYDR/NF-κB signaling pathway.
Volume: 529
Issue: 1
Pages: 35-42
•
•
•
•
•
Publication
28060376 | J:261298
First Author: Schock SN
Year: 2017
Journal: Cell Death Differ
Title: Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway.
Volume: 24
Issue: 4
Pages: 615-625
•
•
•
•
•
Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
•
•
•
•
•
Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
•
•
•
•
•
Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
•
•
•
•
•
Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•
Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
•
•
•
•
•
Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom