| Primary Identifier | MGI:1926264 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 56496 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in negative regulation of canonical NF-kappaB signal transduction and negative regulation of cytoplasmic pattern recognition receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in 1st branchial arch; jaw; and pancreas epithelium. Orthologous to human TSPAN6 (tetraspanin 6). PHENOTYPE: Female mice homozygous for a null allele exhibit enhanced basal synaptic transmission and reduced long term potentiation (LTP) while hemizygous males show abnormal motor learning but no deficits in locomotor behavior or hippocampus-dependent memory tasks. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
