Primary Identifier | MGI:6094862 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(TLR4*D299G)4Haj |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene was generated with a modified version of human genomic BAC RP11-150L1. Using recombineering, an A>G substitution was introduced that resulted in a D299G (p.Asp299Gly) mutation in the translated petide. The copy number of this allele, as determined by RT-PCR, is 4. |