Primary Identifier | MGI:3051640 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ptges |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was replaced with a neomycin resistance gene. Mutant transcripts were detected by Northern blot of peritoneal macrophages. RT-PCR and sequencing confirmed that the mutant transcripts resulted from the deletion of the second exon and that the normal protein was not produced in mutant mice. |