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Allele : Ptges<tm1Aki> prostaglandin E synthase; targeted mutation 1, Shizuo Akira

Primary Identifier  MGI:3051640 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptges
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with a neomycin resistance gene. Mutant transcripts were detected by Northern blot of peritoneal macrophages. RT-PCR and sequencing confirmed that the mutant transcripts resulted from the deletion of the second exon and that the normal protein was not produced in mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • mPGES-1<->,
  • mPGES-1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

45 Publication categories