| Primary Identifier | MGI:5297248 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Gab2 |
| Transmission | Germline | Strain of Origin | C57BL/6Jcl x 129T/SvJcl |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A cDNA encoding amino acids 89-665 was inserted into exon 2, in which nucleotide substitutions that results in the amino acid substitution of phenylalanine for tyrosine at positions 441, 465, and 573 (Y441F, Y465F, Y573F) abolishing the PI3K-binding domain. A floxed neo cassette inserted downstream of exon 2 was removed by cre-mediated recombination. |
